Welsh Transplantation and Immunogenetics Laboratory

Selected publications, posters and articles

Publications in peer reviewed journals
Abstracts of poster presentations
Contributions to books, proceedings and newsletters

Peer reviewed journals:

  1. Darke, C. & Perry, W.N.C. (1976) The use of the IgG fraction of typing sera in the lymphocytotoxic test: a comparison with other cytotoxic methods. Journal of Immunological Methods 13, 381-388.
  2. Darke, C., Orellana, W. & Dodge, J.A. (1976) HLA types and ABO blood groups in infants with pyloric stenosis and their mothers. Tissue Antigens 7, 189-190.
  3. Darke, C. (1977) HLA types and the immune response to the Rh(D) antigen. Tissue Antigens 9, 171-172.
  4. Darke, C., Wagner, M.M.F. & McMillan, G.H.G. (1979) HLA-A and B antigen frequencies in an asbestos exposed population with normal and abnormal chest radiographs. Tissue Antigens 13, 228-232.
  5. Wagner, M.M.F. & Darke, C. (1979) HLA-A and B antigen frequencies in Welsh coalworkers with pneumoconiosis and Caplan's syndrome. Tissue Antigens 14, 165-168.
  6. Darke, C. (1980) Further evidence for the partition of HLA-B14. Tissue Antigens 15, 25-30.
  7. Darke, C. (1980) The first example of an HLA-Bw45 antiserum produced in a HLA-Bw44 positive woman. Tissue Antigens 15, 75-80.
  8. Darke, C. (1980) The HLA-B14 cross-reactive group. Tissue Antigens 15, 389-397.
  9. Darke, C., Wagner, M.M.F., Nuki, G. & Dyer, P.A. (1983) HLA-A, B and DR antigens and properdin factor B allotypes in Caplan's syndrome. Br J Dis Chest 77, 235-242.
  10. Wagner, M.M.F., Darke, C., Coles, R.M. & Evans, C.C. (1983) HLA-A and B antigen frequencies and mesothelioma in relation to asbestos exposure. Br J Cancer 48, 727-730.
  11. Darke, C. (1983) The inclusion of HLA-Bw42, Bw54 and Bw55 within the HLA-B14 cross-reactive group. Tissue Antigens 21, 246-253.
  12. Darke, C. (1983) The HLA-B12 and -B40 cross-reactive groups and their serological relationships. Tissue Antigens 21, 281-295.
  13. Darke, C., Street, J., Sargeant, C. & Dyer, P.A. (1983) HLA-DR antigens and properdin factor B allotypes in responders and non-responders to the Rhesus-D antigen. Tissue Antigens 21, 333-335.
  14. Holt, P.J.A. & Darke, C. (1983) HLA antigens and Bf allotypes in lichen sclerosus et atrophicus. Tissue Antigens 22, 89-91.
  15. Darke, C. (1983) A reanalysis of the HLA-B7 cross-reactive group. Tissue Antigens 22, 326-334.
  16. Darke, C. (1984) Linkage disequilibrium between the HLA-B14 subdivisions and HLA-A, DR and properdin factor B alleles. Tissue Antigens 23, 68-71.
  17. Darke, C. (1984) A serological study of the HLA-B17 cross-reactive group. Tissue Antigens 23, 141-150.
  18. Holt, P.J.A. & Darke, C. (1985) HLA antigens in lichen sclerosus et atrophicus. Clin Exp Dermatol 10, 182-183.
  19. Darke, C. (1985) A F(ab')2 fragment blocking study of the HLA-B14 antigen. Tissue Antigens 25, 177-186.
  20. Amer, A., Singh, G., Darke, C. & Dolby, A.E. (1986) Impaired lymphocyte responsiveness to phytohaemagglutinin associated with the possession of HLA-B8/DR3. Tissue Antigens 28, 193-198.
  21. Darke, C. & O'Neill, G.J. (1987) Association of HLA-Bw65 with two major complotypes. Tissue Antigens 30, 11-17.
  22. Darke, C. & Street, J. (1987) Production of an HLA-DRw13 antibody in a DRw14 positive multiparous woman. Tissue Antigens 30, 42-47.
  23. Giles, C.M., Walport, M.J., David, J. & Darke, C. (1987) Expression of MHC class I determinants on erythrocytes of SLE patients. Clin Exp Immunol 69, 368-374.
  24. Amer, A., Singh, G., Darke, C. & Dolby, A.E. (1987) Cellular immunity to collagen in periodontal disease: role of T, B lymphocytes and adherent cells. J Clin Immunol 24, 183-187.
  25. Amer, A., Singh, G., Darke, C. & Dolby, A.E. (1988) Association between HLA antigens and periodontal disease. Tissue Antigens 31, 53-58.
  26. Cragg, S.J., Darke, C. & Worwood, M. (1988) HLA class I and H-ferritin gene polymorphisms in haemochromatosis. Human Genetics 80, 63-68.
  27. Giles, C.M., Darke, C., Rowe, G. & Botto, M. (1989) HLA class I (Bg) antigens on red cells of SLE patients; a serological study with polyclonal and monoclonal antibodies. Vox Sangunis 56, 254-261.
  28. Young, N.T., Street, J. & Darke, C. (1989) A miniaturised method for immunoglobulin allotype serology. J Immunol Meth 122, 143-147.
  29. Amer, A., Singh, G., Darke, C. & Dolby, A.E. (1990) Spontaneous lymphocyte proliferation in severe periodontal disease: role of T and B cells. Journal of Oral Pathology and Medicine 19, 49-52.
  30. Othman, S., Phillips, D.I.W., Parkes, A.B., Richards, C.J., Harris, B., Fung, H., Darke, C., John, R., Hall, R., Lazarus, J.H. (1990) A long term follow-up of postpartum thyroiditis. Clinical Endocrinology 32, 559-564.
  31. Kologlu, M., Fung, H., Darke, C., Richards, C.J., Hall, R. & McGregor, A.M. (1990) Post-partum thyroid dysfunction and HLA status. European Journal of Clinical Investigation 20, 56-60.
  32. Orchard, J., Young, N.T., Smith, C., Thomas, S. & Darke, C. (1990) Severe intravascular haemolysis in a renal transplant recipient due to anti-B of donor origin. Vox Sangunis 59, 172-175.
  33. Ratanachaiyavong, S., Gunn, C.A., Bidwell, E.A., Darke, C., Hall, R. & McGregor, A.M. (1990) DQA2 U allele: a genetic marker for the relapse of Graves' disease. Clinical Endocrinology 32, 241-251.
  34. Worwood, M., Darke, C. & Trenchard, P.M. (1991) Hereditary haemochromatosis and blood donation. Br Med J 302, 593.
  35. Street, J., Fussell, H., Mills, T. & Darke, C. (1991) A comparison of the reactivity of HLA-Aw33.1 and Aw33.2 with the 10th and 11th Workshop reagents. Tissue Antigens 37, 237-238.
  36. Young, N.T., Mills, M.T., James, S. & Darke, C. (1991) An apparent homozygous example of the HLA-DR2 variant, DR2.4(LUM). Tissue Antigens 38, 41-44.
  37. Young, N.T. & Darke, C. (1993) "Molecular crossmatching" for allogeneic bone marrow transplants by DNA single-strand polymorphism analysis. Lancet 341, 183-184.
  38. Worwood, M & Darke, C. (1993) Serum ferritin, blood donation, iron stores and haemochromatosis. Transfusion Medicine 3, 21-28.
  39. Ratanachaiyavong, S., Lloyd, L., Darke, C. & McGregor, A.M. (1993) MHC-extended haplotypes in families of patients with Graves' disease. Human Immunology 36, 99-111.
  40. Young, N.T. & Darke, C. (1993) Allelic typing of the HLA- DR4 group by polymerase chain reaction-single strand conformation polymorphism analysis. Human Immunology 37, 69-74.
  41. Young, N.T. & Darke, C. (1994) Molecular characterization of the HLA-DR2LUM haplotype. Tissue Antigens 43, 28-33.
  42. Young, N.T. & Darke, C. (1994) Gene frequency and linkage disequilibrium analysis of HLA-DRB1*04 haplotypes in a South Wales population. European Journal of Immunogenetics 21, 15- 22.
  43. Fussell, H., Thomas, M., Street, J. & Darke, C. (1994) Serological identification of a new HLA-B7 variant antigen - HLA-B7QUI. European Journal of Immunogenetics 21, 23-31.
  44. Worwood, M., Raha-Chowdhury, R., Dorak, M.T., Darke, C., Bowen, D.J. & Burnett, A.K. (1994) Alleles at D6S265 and D6S105 define a haemochromatosis-specific genotype. British Journal of Haematology 86, 863-866.
  45. Hildebrand, W.H., Domena, J.D., Shen, S.Y., Marsh, S.G., Marsh, S.G., Bunce, M., Guttridge, M.G., Darke, C. & Parham, P. (1994) The HLA-B7Qui antigen is encoded by a subtype of HLA-B27 (B*2708). Tissue Antigens 44, 47-51.
  46. Worwood, M., Raha-Chowdhury, R., & Darke, C. (1994) Distribution of alleles at D6S105 and D6S265 with possible HLA haplotype associations. Tissue Antigens 44, 322-325.
  47. Jahn, I., Mejia, J.E., Thomas, M., Darke, C., Schroder, H., Geserick, G. & Hauptman, G. (1994) Genomic analysis of the F subtypes of human complement factor B. European Journal of Immunogenetics 21, 415-423.
  48. Young, N.T., Thompson, J., Gibson, K., Dewar, K. & Darke, C. (1995) Immunogenetic analysis of HLA-DR10 homozygous individuals. European Journal of Immunogenetics 22, 191-197.
  49. Guttridge, M. G., Thompson, J., Burr, C. & Darke, C. (1995) The differentiation of HLA-B*1401 (B64) and B*1402 (B65) by the polymerase chain reaction using sequence-specific primers (PCR-SSP). Tissue Antigens 45, 213-215.
  50. Young, N.T., Street, J. & Darke, C. (1995) Immunoglobulin allotype frequencies in responders and nonresponders to the Rh(D) antigen. Experimental and Clinical Immunogenetics 12, 88-91.
  51. Arnett, K.L., Adams, E.J., Gumperz, J.E., Darke, C., Marsh, S.G.E., Gelsthorpe, K, Parham, P. (1995) Expression of an unusual Bw4 epitope by a subtype of HLA-B8 [B*0802]. Tissue Antigens 46, 316-321.
  52. Fussell, H., Thomas, M., Street, J. & Darke (1996) HLA-A9 antibodies and epitopes. Tissue Antigens 47, 307-312.
  53. Worwood, M., Dorak, M.T., Nicklin, S., Stone, C., Pointon, J. & Darke, C. (1996) The frequency of the haemochromatosis-associated genotype D6S265-1:D6S105-8 in blood donors. British Journal of Haematology 93, 838-840.
  54. Parkes, A.B., Darke, C., Othman, S., Thomas, M., Young, N., Richards, C.J., Hall, R., Lazarus, J.H. (1996) MHC class II and complement polymorphisms in postpartum thyroiditis. European Journal of Endocrinology 134, 449-453.
  55. Thomas, M., Street, J., Fussell, H., Guttridge, M. & Darke, C. (1996) Distribution of the HLA-A9 antigen family (A23, A24 and A2403). Tissue Antigens 48, 586-588.
  56. Darke, C., Fussell, H., Street, J., Thomas, M., Guttridge, M.G., Worwood, M. (1996) Serological and molecular identification of an HLA-B8 variant - HLA-B8Jon [B*0802]. Experimental and Clinical Immunogenetics 13, 139-153.
  57. Guttridge, M.G., Hudson, L., Williams, H., Dunn, P., Day, S. & Darke, C. (1997) Identification and nucleotide sequence of two novel DRB3 alleles, DRB3*0102 and DRB3*010133. Tissue Antigens 49, 665-667.
  58. Darke, C., Street, J., Fussell, H., Thomas, M., Guttridge, M., Goldberg, T.E. Arnett, K.L. & Parham, P. (1997) A new HLA-B44 variant (B44BO [B*4408]) identified by serology. Tissue Antigens 50, 32-37.
  59. Worwood, M., Raha Chowdhury, R., Robson K.J.H., Pointon, J., Shearman, J.D. & Darke, C. (1997) The HLA A1-B8 haplotype extends 6 Mb beyond HLA-A: associations between HLA-A, B, F and 15 microsatellite markers. Tissue Antigens 50, 521-526.
  60. Finch, T., Lawlor, E., Borton, M., Barnes, C.A., McNamara, S., O'Riordan, J., McCann, S.R. & C. Darke (1997) Distribution of HLA-A, B and DR genes and haplotypes in the Irish population. Experimental and Clinical Immunogenetics 14, 260-263.
  61. Coates, E. & Darke, C. (1998) Routine HLA-B27 typing by flow cytometry - differentiation of the products of HLA- B*2702, B*2705, and B*2708. European Journal of Immunogenetics 25, 29-38.
  62. Darke, C., Guttridge, M.G., Thompson, J., Street, J., Thomas, M. (1998) Molecular, serological and population studies on a novel HLA-B allele - HLA-B*5002. Tissue Antigens 51, 666-670.
  63. Darke, C., Guttridge, M.G., Thompson, J., McNamara, S., Street, J. & Thomas, M. (1998) HLA class I (A,B) and II (DR,DQ) gene and haplotype frequencies in blood donors from Wales. Experimental and Clinical Immunogenetics 15, 69-83.
  64. Long, C.C., Darke, C., Marks, R. (1998) Celtic ancestry, HLA phenotype and increased risk of skin cancer. British Journal of Dermatology 138, 627-630.
  65. Guttridge, M.G., Thompson, J., Worwood, M., Darke, C. (1998) Rapid detection of genetic mutations associated with haemochromatosis. Vox Sangunis 75, 253-256.
  66. Guttridge, M.G., Street, J., Thomas, M. & Darke, C. (1999) Identification of HLA-A*0224: Implications for PCR-SSP HLA typing. Tissue Antigens 53, 190-193.
  67. Guttridge, M.G., Thompson, J., Street, J. & Darke, C. (1999) Identification, sequencing and serology of HLA- B*3527. Tissue Antigens 53, 383-385.
  68. Sheppard, D., McPhee, D., Darke, C., Shrethra, B., Moore, R., Jurewitz, A. & Gray, A. (1999) Predicting cytomegalovirus disease after renal transplantation: an artificial neural network approach. International Journal of Medical Informatics 54, 55-76.
  69. Darke, C., Guttridge, M.G., Street, J., Thompson, J. & Thomas, M. (1999) HLA-B*4703: sequence confirmation, serology and distribution. Tissue Antigens 53, 586-590.
  70. Darke, C., Winkler, S., Guttridge, M.G., Street, J., Thomas, M., Thompson, J., McNamara, S. (1999) Molecular, serological and population studies of the alleles and products of HLA-B*41. Experimental and Clinical Immunogenetics 16, 139-149.
  71. Smyth, P.P., Darke, C., Parkes, A.B., Smith, D.F., John, R., Hetherton, A.M., Lazarus, J.H. (1999) Assessment of goiter in an area of endemic iodine deficiency. Thyroid 9, 895-901.
  72. Sellers, J., Thompson, J., Guttridge, M.G. & Darke, C. (1999) Human platelet antigens: typing by PCR using sequence-specific primers and their distribution in blood donors resident in Wales. European Journal of Immunogenetics 26, 393-397.
  73. Darke, C. (2000) An overview of the Welsh bone marrow Donor Registry: ten years of bone marrow donor provision. bone marrow Transplantation 25, 771-777.
  74. Darke, C., Guttridge, M.G., Street, J., Thompson, J. & Thomas, M. (2000) Molecular, serological and genetic studies on two new HLA-DRB1 alleles - HLA-DRB1*0704 and HLA-DRB1*1507. Tissue Antigens 56, 467-469.
  75. Guttridge, M.G., Carter, K., Worwood, M. & Darke, C. (2000) Population screening for hemochromatosis by PCR using sequence specific primers. Genetic Testing 4, 111-114.
  76. Bonar, B.D., McColgan, B., Smith, D.F., Darke, C., Guttridge, M.G., Williams, H. & Smyth, P.P.A (2000) Hypothyroidism and ageing: The Rosses' survey. Thyroid 10, 821-827.
  77. Guttridge, M.G. & Darke, C. (2001) Identification and nucleotide sequence of HLA-A*02015. Tissue Antigens 57, 469-470.
  78. Darke, C., Street, J. & Guttridge, M.G (2001) Sequence, genetics and serology of a new HLA-B allele: B*4903. Tissue Antigens 57, 478-480.
  79. Guttridge, M.G. & Darke, C. (2001) Identification and nucleotide sequence of HLA-A*03013. Tissue Antigens 57, 546-547.
  80. Williams, F., Meenagh, A., Darke, C., Acosta, A., Daar, A.S., Gorodezky, C., Hammond, M., Nascimento, E. & Middleton, D. (2001) Analysis of the distribution of HLA-B alleles in populations from five continents. Human Immunology 62, 645-650.
  81. Jackson, H., Carter, K., Darke, C., Guttridge, M., Ravine, D., Hutton, R.D., Napier, J.A. & Worwood, M. (2001) HFE mutations, iron deficiency and overload in 10,500 blood donors. British Journal of Haematology 114, 474-484.

 

 

(Page Index)

Peer reviewed abstracts of poster presentations:

Selected posters from WTAIL are available in the form of a PowerPoint® poster.
The posters are stored in .pdf format which may be viewed using Adobe® Acrobat®

If a Reader is not installed, click on Get Acrobat® Reader to download the free software

. Acrobat download link

Click on the View poster button alongside the Poster number to view the presentation,
then click on Acrobat's + or - zoom buttons to read the poster online.

 

  1. Trenchard, P.M., Darke, C. & Peake, I.R. (1977) Autoimmune disease induced by a paraprotein with specific antibody activity. British Journal of Haematology 36, 446.
  2. Kologu, M., Fung, H., Darke, C., Richards, C.J., Hall, R.& McGregor, A.M. (1986) Post-partum thyroid dysfunction and HLA status. J Endocrinol Invest (suppl. 3) 9, 114.
  3. Young, N.T., Mills, M.T., James, S., Thompson, J., Shipman, A., Gibson, K. & Darke, C. (1991) Molecular analysis of the HLA-DR2 variant, DR2.4LUM. European Journal of Immunogenetics 18, 232.
  4. Gibson, K., Young, N.T., Thompson, J. & Darke, C. (1991) The HLA-DRw14b allele is present at low frequency in the indigenous Welsh population. European Journal of Immunogenetics 19, 81.
  5. Young, N.T., Thompson, J., Gibson, K. & Darke, C. (1991) Definition of HLA-DRB RFLPs in three DRw10 homozygous individuals. European Journal of Immunogenetics 19, 82.
  6. Rees, T., Young, N.T., Thompson, J., Gibson, K. & Darke, C. (1991) A comparison of HLA-DR typing of renal transplant donors and recipients by serological and RFLP methods. European Journal of Immunogenetics 19, 83.
  7. Young, N.T. & Darke, C. (1991) Immunoglobulin allotypes and immune responsiveness to RhD antigen. European Journal of Immunogenetics 19, 84.
  8. Darke, C., Thomas, M., Young, N., Lazarus, J.H., Othman, S., Parkes, A.B., Richards, C.J. & Hall, R. (1992) Postpartum thyroid disease - are class II antigens important in pathogenesis? J Endocrinol 132 (suppl.), 327.
  9. Darke, C., Thomas, M., Young, N., Othman, S., Lazarus, J. & Richards, C. (1992) Postpartum thyroid disease - are class II and class III antigens important? J Endocrinol Invest 15 (suppl. 2), 65.
  10. Thomas, M.W. & Darke, C. (1992) Distribution of anti- epithelial cell antibodies in normal blood donors. European Journal of Immunogenetics 19, 453.
  11. Thomas, M.W. & Darke, C. (1992) Subtypes of BFF (BFFa and BFFb) - Frequency and linkage disequilibrium with HLA- B and DR alleles. European Journal of Immunogenetics 19, 454.
  12. Fussell, H. & Darke, C. (1992) HLA-B7QUINN - A new HLA-B7 variant antigen. European Journal of Immunogenetics 19, 449.
  13. Young, N.T., Thompson, J. & Darke, C. (1992) HLA DR2LUM possible genetic origin through recombination between HLA DR1 and HLA DR15 haplotypes - European Journal of Immunogenetics 19, 451.
  14. Young, N.T. & Darke, C. (1992) Frequency and association of HLA-DR4 alleles in a South Wales population. European Journal of Immunogenetics 19, 450.
  15. Young, N.T. & Darke, C. (1992) Single strand conformational polymorphism analysis (PCR-SSCP) analysis of the HLA-DR4 alleles. European Journal of Immunogenetics 19, 452.
  16. Sage, D.A., Howell, W.M., Darke, C., Taylor, G.M., Yin, J.L., Avakian, H, Kaminski, E., Batchelor, J.R. & Goldman, J.M. (1993) Incidence of HLA-DPB1 mismatches in a series of HLA-A,B and DR serologically matched related and unrelated bone marrow transplant pairs. Human Immunology 36, 62.
  17. Sage, D.A., Howell, W.M., Darke, C., Taylor, G.M., Yin, J.L., Jaminski, E., Batchelor, J.R. & Goldman, J.M. (1993) Incidence of HLA-DPB1 mismatches in a series of HLA-A,B and DR serologically matched related and unrelated bone marrow transplant pairs. Human Immunology 37, suppl 1, 88.
  18. Sage, D.A., Howell, W.M., Darke, C., Taylor, G.M., Yin, J.L., Avakian, H., Batchelor, J.R. & Goldman, J.M. (1993) Incidence of HLA-DPA1 and HLA-DPB1 mismatches in a series of HLA-A,B and DR serologically matched related and unrelated bone marrow transplant pairs. European Journal of Immunogenetics 20, 479.
  19. Fussell, H., Street, J., Thomas, M. & Darke (1993) HLA- B8JON - a possible variant of HLA-B8. European Journal of Immunogenetics 20, 498.
  20. Lazarus, J.H., Smyth, P.A., Parkes, A.B., Darke, C., N'Diaye, A.M. (1993) Are immunological factors involved in the pathogenesis of endemic goitre in Senegal? J Endocrinology 137, 209.
  21. Dorak, M.T. & Darke, C. (1994) Age and sex-specific HLA DQA1 gene and genotype frequencies. Human Immunology 40, suppl. 1, 100.
  22. Jahn, I., Mejia, J.E., Thomas, M., Darke, C., Schroder, H., Geserick. & Hauptman, G. (1994) 5' end molecular definition of Bf alleles. Clinical and Experimental Immunology 97, suppl. 2, 28.
  23. Reynolds, W.M., Evans, P.R., Hemmatpour, S.K., Wong, W.M., Howell, W.M. & Darke, C. (1994) Two years experience of automated HLA-B27 typing using the FACSPREP/FACSCAN system. Human Imunology 40, suppl. 1, 168.
  24. Guttridge, M.G., Thompson, J. & Darke, C. (1995) The differentiation of HLA-B*1401 (B64) and B*1402 (B65) by the polymerase chain reaction using sequence specific primers (PCR-SSP). European Journal of Immunogenetics 22, 101.
  25. Sellers, J., Guttridge, M.G. & Darke, C. (1995) An improved method of PCR-SSP HPA-1 typing. European Journal of Immunogenetics 22, 102.
  26. Reynolds, W.M., Evans, P.R., Wilson, P.J. & Darke, C. (1995) Automated routine HLA-B27 typing by flow cytometry. European Journal of Immunogenetics 22, 111.
  27. Fussell, H., Thomas, M., Street, J. & Darke, C. (1995) HLA-A9 antibodies and epitopes. European Journal of Immunogenetics 22, 134.
  28. Street, J., Fussell, H., Thomas, M. & Darke, C. (1995) HLA-B44BO - a possible variant of B44. European Journal of Immunogenetics 22, 136.
  29. Thomas, M., Street, J., Fussell, H. & Darke, C. (1995) Identification of HLA-A23, -A24, and -A2403 in 9196 unrelated bone marrow donors - serology and frequencies. European Journal of Immunogenetics 22, 136.
  30. Dorak, M.T. & Darke C. (1995) Molecular heterogeneity of the HLA-A*0301 haplotypes. Human Immunology 44, suppl. 1 11.
  31. Dorak, M.T. & Darke C. (1995) Consequences of HLA associations with lethal diseases in the population. Human Immunology 44, suppl. 1, 74.
  32. Smyth, P.P.A., Darke, C., Parkes, A.B., Hetherton, A.M., Smith, D.F. & Lazarus, J.H. (1995) Lack of HLA restriction in the pathogenesis of endemic goitre in an African population. J Endocrinology 144, 170.
  33. Smith, D.F., Darke, C., Parkes, A.B., Hetherton, A.M. & Lazarus, J.H. (1995) The pathogenesis of endemic goitre in an African population. Thyroid 5, suppl. 1, S-39.
  34. Thompson, J., Guttridge, M.G. & Darke C. (1996) Frequency and linkage disequilibrium with HLA-B of the non- serologically defined HLA-Cw alleles. European Journal of Immunogenetics 23, 78 (2.1).
  35. Guttridge, M.G. & Darke C. (1996) Rare DRB1 and DQB1 haplotypes identified in 2908 random blood donors. European Journal of Immunogenetics 23, 78 (2.2).
  36. Guttridge, M.G., Williams, H., Day, S., Smyth, P.P.A., Ross, J., Bonar, B.D. & Darke, C. (1996) Identification of a new HLA-DRB3 allele (DRB3*MOBD) by PCR-SSP and DNA sequencing. European Journal of Immunogenetics 23, 79.
  37. Dorak, M.T. & Darke, C. (1996) Homozygosity for HLA-DR52 and DR53 haplotypes show opposite trends in the normal population. European Journal of Immunogenetics 23, 84.
  38. Bonar, B.D., McColgan, B., Smith, D.F., Darke, C., Guttridge, M.G., Williams, H. & Smyth, P.P.A (1996) Hypothyroidism in a general practice: an stadair s'na' Rossan (the Rosses' survey). Journal of Endocrinology 148, suppl. OC32.
  39. Sage, D., Darke, C., Taylor, M., Howell, M. (1996) HLA-DP mismatching in HLA-A, B, DR and DQ identical patient sibling donor (ID-BMT) bone marrow transplantation. Human Immunology 47, 83.
  40. Long, C.C., Darke, C. & Marks, R. (1996) Celtic ancestry, HLA phenotype and increased risk of skin cancer. British Journal of Dermatology 135, suppl. 47, 23-24.
  41. O'Reilly, F.M., Spencer, S., Darke, C. & Murphy, G.M. (1996) HLA-DR4 B1*0407 - strong association with actinic prurigo in Ireland. British Journal of Dermatology 135, suppl. 47, 65.
  42. Dorak, M.T., Darke, C., Schaaf, A., Machulla, H.K.G., Mills, K.I. & Burnett, A.K. (1996) A gender effect in HLA association with childhood leukemia. Human Immunology 49, suppl. 1, 64.
  43. Dorak, M.T., McKinna, F., Schaaf, A., Machulla, H.K.G., Darke, C., Burnett, A.K. & Barrett-Lee, P. (1996) Major histocompatibility complex and breast cancer. Human Immunology 49, suppl. 1, 70.
  44. Winkler, S., Guttridge, M.G., Street, J., Thomas, M., Thompson, J., McNamara, S. & Darke, C. (1997) Molecular, biochemical, serological and population study of HLA- B*4101 and B*4102. European Journal of Immunogenetics 24, 36.
  45. Rees, T., Guttridge, M.G., Street, J., Thomas, M., Thompson, J., Eyres, R., Rees, M.T. & Darke, C. (1997) Identification and distribution of HLA-B*15 alleles in a random population. European Journal of Immunogenetics 24, 36.
  46. Guttridge M.G., Hudson, L., Dunn, P., Day, S., Thompson, J. and Darke, C. (1997) Identification and nucleotide sequence of a novel DRB3 allele, DRB3*N409. European Journal of Immunogenetics 24, 40.
  47. Street, J., Thomas, M., Rees, T., Rees, M.T., Blayney, J.D.M. & Darke, C. (1997) Incidence of HLA-B27 and -B7QUI (B*2708) in routine patient requests for B27-associated disease typing. European Journal of Immunogenetics 24, 48.
  48. Gray, A., Sheppard, D., Darke, C., Shrestha, B., Moore, R. & McPhee, D. (1997) A single centre study into the influence of HLA matching on renal allograft transplantation. European Journal of Immunogenetics 24, 53.
  49. Coates, E., Rees, M.T., Moore, R., & Darke, C. (1997) Retrospective analysis by flow cytometry of 82 cytotoxic cross-match negative renal transplants. European Journal of Immunogenetics 24, 55.
  50. Downing, J., Rees, M.T., Coates, E. & Darke, C. (1997) Comparison of peripheral blood and spleen lymphocytes in the cytotoxic cross-match prior to renal transplantation. European Journal of Immunogenetics 24, 57.
  51. Gray, A., Sheppard, D., Moore, R., Darke, C., Shrestha, B., Ware, A. & McPhee, D. (1997) Development of an artificial neural network for use in renal transplant decision making. European Journal of Immunogenetics 24, 62.
  52. Coates, E. & Darke, C. (1997) HLA-B27 (including B*2708) typing by flow cytometry. European Journal of Immunogenetics 24, 73.
  53. Dorak, M.T., Lawson, T.M., Parsons, A., Darke, C. & Burnett, A.K. (1998) A deficit of homozygosity for HLA- DRB4*01 in Welsh newborn boys. European Journal of Immunogenetics 25, (2.9) 54.
  54. Dorak, M.T., Parsons, A. & Darke, C. (1998) Genetic epidemiology of homozygosity for HLA-DRB4*01 (DR53) and its haplotypes. European Journal of Immunogenetics 25, (2.10) 54.
  55. Rees, M.T., Howells, K., McNamara, S., Eyres, R., Powell, D., McGregor, M., Walters, R., Darke, C. (1998) Profile of Welsh bone marrow donor registry volunteers who have donated bone marrow. European Journal of Immunogenetics 25, (7.3) 67.
  56. Rees, M.T., McGregor, M., Guttridge, M.G., Thompson, J., Walters, R., Eyres, R., McNamara, S. & Darke, C. (1998) Current status of the Welsh bone marrow Donor Registry volunteer panel - HLA typing quality, demography, CMV status, attrition. European Journal of Immunogenetics 25, (9.4) 69.
  57. Thompson, J., Street, J., Guttridge, M.G., Thomas, M. & Darke, C. (1998) Comparison of serological and PCR-SSP HLA-A and B specificity assignment on 1798 subjects. European Journal of Immunogenetics 25, (10.3) 72.
  58. Guttridge, M.G., Day, S., Dunn, P. & Darke, C. (1998) Identification of HLA-A*0224: Implications for PCR-SSP HLA typing. European Journal of Immunogenetics 25, (10.4) 72.
  59. Guttridge, M.G., Thompson, J., Worwood, M. & Darke, C. (1998) Rapid detection of genetics mutations associated with haemochromatosis. European Journal of Immunogenetics 25, (10.5) 73.
  60. Thompson, J., Street, J., Guttridge, M.G. & Darke, C. (1998) HLA-A*2502 - frequency and serology of the product. European Journal of Immunogenetics 25, (12.2) 77.
  61. Thompson, J., Street, J., Thomas, M., Guttridge, M.G. & Darke, C. (1998) HLA-B*5002-sequence confirmation, population studies & serology. European Journal of Immunogenetics 25, (12.4) 77.
  62. Darke, C., McNamara, S., Guttridge, M.G., Thompson, J., Street, J. & Thomas, M. (1998) HLA-A, B, DR, DQ gene and haplotype frequencies in blood donors from Wales. European Journal of Immunogenetics 25, (12.7) 79.
  63. Thompson, J., James, D., Street, J., Bass, H., Thomas, M., Guttridge, M.G. & Darke, C. (1999) HLA-A2 alleles in Wales: detection, distribution and serology. European Journal of Immunogenetics 26, (1.4) 47.
  64. Street, J., Thompson, J., Thomas, M., Guttridge, M.G. & Darke, C. (1999) HLA-B*4703: sequence confirmation, serology and distribution. European Journal of Immunogenetics 26, (1.5) 48.
  65. Guttridge, M.G., Thompson, J., Street, J. & Darke, C. (1999) Identification, sequencing and serology of a new HLA-B*35 allele, B*35JAC. European Journal of Immunogenetics 26, (2.3) 49.
  66. Dorak, M.T., Darke, C., Mills, K.I. & Burnett, A.K. (1999) A molecular investigation of linkage disequilibrium within three regions of the major histocompatibility complex. European Journal of Immunogenetics 26, (2.4) 50.
  67. Walters, R., Coates, E., Rees, T., Bass, H., Winkler, S., Downing, J., Rees, M.T. & Darke, C. (1999) Comprehensive renal patient antibody screening by cytotoxicity, flow cytometry and ELISA. European Journal of Immunogenetics 26, (6.2) 58.
  68. Darke, C., Guttridge, M.G., Thompson, J., Street, J., Thomas, M., Dunn, P., Day, S., McNamara, S. and Ross, J. (1999) Frequency and linkage disequilibra of HLA-DRB1, DQB1 and DPB1 alleles in blood donors from Wales. European Journal of Immunogenetics 26, (7.5) 62.
  69. Sheppard, D., Darke, C., Street, J., McPhee, D. & Davies, C. (1999) A computer support system for the analysis of HLA class-I amino acid sequences. European Journal of Immunogenetics 26, (10.6) 68.
  70. Bass, H., Walters, H. & Darke, C. (1999) Preparation of Epstein-Barr virus transformed B-lymphocyte cell line pools for antibody screening by flow cytometry. European Journal of Immunogenetics 26, (10.14) 72.
  71. Sellers, J., Thompson, J., Bass, H., Eyres, R., Guttridge, M.G. & Darke, C. (1999) DNA typing and phenotype distribution of the HPA system in blood donors from Wales. European Journal of Immunogenetics 26, (12.3) 76.
  72. Abideen, S., Darke, C., Guttridge, M.G., Thompson, J., Rolf, S., Sting, C., Davies, B.H. (1999) Distribution of HLA-A, B, DR and DQ specificities in nut allergy patients. Allergy 54, suppl. 52, 181.
  73. Dorak, M.T., Machulla, H.K.G., Darke, C., Poynton, C.H., Barrett-Lee, P & Burnett, A.K. (1999) Overall homozygosity for HLA class II supertypes is increased in malignancies. Human Immunology 60, suppl. 2, S13.
  74. Dorak, M.T., Darke, C. & Poynton, C.H. (1999) Molecular analysis of the MHC in Hodgkin's disease: association with a supertypical homozygous genotype. Human Immunology 60, suppl. 2, S70.
  75. Jackson, H., Carter, K., Guttridge, M., Darke, C., Napier, A., Ravine, D. & Worwood, M. (1999) Haemochromatosis- prevalence and penetrance in blood donors resident in Wales. Blood 94, (S1), 407a.
  76. Guttridge, M.G., Rees, T. & Darke, C. (1999) HLA-A, -B, -DR and -DQ typing of Welsh bone marrow Donor Registry Panel Donors by PCR using sequence specific primers. Transfusion Medicine 9, (Suppl 1-P32), 35.
  77. Coates, E., Sellers, J., Rees, T. & Darke, C. (1999) Routine serological analysis of 188 cases of alleged idiopathic thrombocytopenic purpura (ITP). Transfusion Medicine 9, (Suppl 1-P33), 35.
  78. Rees, T., Coates, E., Winkler, S., Guttridge, M.G. & Darke, C. (1999) Differentiation of common HLA-B*27 alleles by flow cytometry. Transfusion Medicine 9, (Suppl 1-P34), 35.
  79. Jackson, H., Carter, K., Guttridge, M., Darke, C., Napier, A., Ravine, D. & Worwood, M. (2000) Haemochromatosis - HFE mutations and iron status in 10,000 blood donors from South Wales. British Journal of Haematology 108 (S1), 47.
  80. View poster 80Street, J., Guttridge, M.G., Thomas, M. & Darke, C. (2000)
    Sequence, genetics and serology of a new HLA allele - HLA- B*"RA".
    European Journal of Immunogenetics 27, (2.4) 259.
  81. View poster 81Guttridge, M. G., Street, J., Thompson, J. & Darke, C. (2000)
    Molecular, serological and genetic studies on two new HLA-DRB1 alleles - DRB1*0704 and - DRB1*1507
    European Journal of Immunogenetics 27, (2.7) 260.
  82. View poster 82Darke, C., Guttridge, M.G., Carter, K., McNamara, S., Napier, J.A.F. & Worwood, M. (2000)
    Distribution of HFE alleles and HLA/HFE haplotypes in blood donors resident in Wales.
    European Journal of Immunogenetics 27, (5.3) 263.
  83. View poster 83Rees, T., Coates, E., Winkler, S., Guttridge, M.G. & Darke, C. (2000)
    The distribution of HLA-B*27 alleles is the same in HLA-B27 positive patients and healthy blood donors
    European Journal of Immunogenetics 27, (5.5) 264.
  84. View poster 84Rees, M. T. & Darke, C. (2000)
    Incidence of HLA-C mismatches in "favourably matched" renal transplant patients matched for HLA-B specificities
    European Journal of Immunogenetics 27, (6.6) 268.
  85. View poster 85Downing, J., Guttridge, M.G. & Darke, C. (2000)
    HA-1 typing in unrelated bone marrow panel donors resident in Wales.
    European Journal of Immunogenetics 27, (6.8) 269.
  86. View poster 86Rees, M. T. & Darke, C. (2000)
    HLA-A, B, C, DR and DQ "split" specificity level matching in HLA-A,B,DR "favourably matched kidney recipients.
    European Journal of Immunogenetics 27, (6.11) 270.
  87. View poster 87Darke, C. & Eyres, R. (2000)
    An analysis of unique HLA phenotypes in the Welsh bone marrow Donor Registry.
    European Journal of Immunogenetics 27, (7.15) 282.
  88. View poster 88Walters, R., Williams, H., Downing, J., Hammond, L., Bass, H., Winkler, S. & Darke, C. (2000)
    Comparison between cytotoxicity, flow cytometry and two ELISA kits for renal patient HLA-class I and II antibody screening.
    European Journal of Immunogenetics 27, (8.16) 290.
  89. View poster 89Guttridge, M. G., Carter, K., Worwood, M. & Darke, C. (2000)
    Population screening for haemochromatosis by PCR using sequence-specific primers.
    European Journal of Immunogenetics 27, (8.18) 291.
  90. View poster 90Coates, E. & Darke, C. (2000)
    An evaluation of "Com-B27" a fluorescein conjugated mouse anti-HLA-B27 reagent.
    European Journal of Immunogenetics 27, (8.19) 291.
  91. View poster 91Bass, H., Guttridge, M. G. & Darke, C. (2000)
    Mycoplasma testing of Epstein-Barr virus transformed B-lymphocytes cell lines.
    European Journal of Immunogenetics 27, (8.24) 294.
  92. Darke, C., Guttridge, M.G., Thompson, J. & McNamara, S. (2000)
    Frequency and linkage disequilibrium of alleles from five HLA-class II loci in blood donors from Wales.
    European Journal of Immunogenetics 27, (10.22) 305.
  93. View poster 93Darke, C. Guttridge, M. G., Thompson, J., Eyres, R., Wijeyratne, C.N., Premawardhana, L.D.K.E. & Lazarus, J. H. (2000)
    HLA-A, B, DR and DQ gene and haplotype frequencies in Sri Lanka.
    European Journal of Immunogenetics 27, (10.24) 306.
  94. View poster 94Rees, T. J., Mohabir, L. A. & Darke, C. (2000)
    Distribution of HLA specificities in IgA deficient (IgA-D) blood donors resident in Wales.
    European Journal of Immunogenetics 27, (10.26) 307.
  95. View poster 95Darke, C., Eyres, R., Thompson, J. & Guttridge, M. G. (2000)
    Beware researchers bearing gifts - a cautionary tale.
    European Journal of Immunogenetics 27, (10.28) 308.
  96. Rees, T.J., Coates, E., Williams, H. & Darke, C. (2000)
    Evaluation of a new mouse monoclonal antibody reagent ("Com-B27") for flow cytometry HLA-B27 testing.
    Transfusion Medicine 10, (Suppl 1-P41), 34.
  97. Hambley, H., McGregor, M., Powell, D., Rees, T.J. & Darke, C. (2000)
    An analysis of bone marrow donation requests to the Welsh bone marrow Donor Registry (WBMDR) that did not proceed to donation.
    Transfusion Medicine 10, (Suppl 1-P85), 46.
  98. View poster 98Street, J., Guttridge, M.G., Thompson, J., Hammond, L., Downing, J. & Darke, C. (2001)
    Sequence, genetics & serology of a new HLA allele - HLA-B*2723.
    European Journal of Immunogenetics 28, (1.3) 472.
  99. Darke, C., Street, J. & Guttridge, M.G. (2001)
    HLA-B*4408: Confirmatory sequence, genetics and serology.
    European Journal of Immunogenetics 28, (1.4) 472.
  100. Rees, M.T., Keen, L.J., Bidwell, J.L. & Darke, C. (2001)
    TNFa and TNFd microsatellite frequencies and linkage disequilibrium with HLA-B and -DR in renal transplant recipients.
    European Journal of Immunogenetics 28, (2.2) 473.
  101. Darke, C., Guttridge, M.G. & Thompson, J. (2001)
    Frequency of HLA-DRB1*01 and DRB1*04 alleles in the blood donor population resident in South Wales.
    European Journal of Immunogenetics 28, (2.5) 475.
  102. Rees, M. T. & Darke, C. (2001)
    HLA-DRB1 and DQB1 allele mismatching in ‘favourably matched’ renal transplant patients.
    European Journal of Immunogenetics 28, (6.4) 480.
  103. McGregor, M., Hambley, H., Powell, D. & Darke, C. (2001)
    An analysis of bone marrow donation requests to the Welsh bone marrow Donor Registry that did not proceed to donation.
    European Journal of Immunogenetics 28, (7.4) 484.
  104. View poster 104Downing, J., Guttridge, M.G. & Darke, C. (2001)
    A modified PCR-SSP method for the identification of ABO blood group antigens.
    European Journal of Immunogenetics 28, (8.5) 488.
  105. Coates, E., Rees, T.J., Winkler, S., Cleaton, A. & Darke, C. (2001)
    Routine experience of "Com-B27" fluorescein conjugated mouse anti-HLA-B27 reagent.
    European Journal of Immunogenetics 28, (8.11) 491.
  106. Walters, R. & Darke, C. (2001)
    ELISA screening and identification kit findings on cytotoxicity negative renal sera.
    European Journal of Immunogenetics 28, (8.14) 493.
  107. View poster 107Hammond, L., Guttridge, M.G. & Darke, C. (2001)
    A modified RSCA method for low-resolution HLA-C typing.
    European Journal of Immunogenetics 28, (8.19) 495.
  108. View poster 108Bass, H., Guttridge, M.G. & Darke, C. (2001)
    An evaluation of routine Epstein-Barr virus transformation of B-lymphocytes.
    European Journal of Immunogenetics 28, (8.20) 496.
  109. View poster 109Darke, C. & Corbin S. (2001)
    Accuracy of HLA typing in the United Kingdom & Republic of Ireland - 1995-2000.
    European Journal of Immunogenetics 28, (10.4) 500.
  110. View poster 110Darke, C., Guttridge, M.G., Thompson, J., Eyres, R., Wijeyratne, C. N., Premawardhana, L.D.K.E. & Lazarus, J. H. (2001)
    HLA, HPA and HFE polymorphisms in Sri Lanka.
    European Journal of Immunogenetics 28, (10.6) 501.
  111. View poster 111Street, J., Guttridge, M.G., Thompson, J. & Darke, C. (2001)
    Genetics, serology and sequences of six low frequency HLA-Class I alleles.
    European Journal of Immunogenetics 28, (10.7) 502.
  112. View poster 112Darke, C., Street, J., Guttridge, M.G., Thompson, J. & Hammond, L. (2001)
    Distribution of HLA-B27 and B2708 in the Welsh bone marrow Donor Registry panel and likely B*2708 bearing haplotypes.
    European Journal of Immunogenetics 28, (10.8) 502.
  113. View poster 113Street, J., Hammond, L., Thompson, J. & Darke, C. (2002)
    Serological characterisation of the products of nine rare HLA class I alleles.
    European Journal of Immunogenetics 29, 355 (1.1).
  114. View poster 114Street, J., Hammond, L., Downing, J., Thompson, J. & Darke, C. (2002)
    Observations on the HLA-A2403 specificity.
    European Journal of Immunogenetics 29, 356 (2.4).
  115. View poster 115Hammond, L., Street, J., Downing, J., Thompson, J. & Darke, C. (2002)
    HLA-A and -B null alleles in 6,528 subjects resident in Wales.
    European Journal of Immunogenetics 29, 356 (2.5).
  116. View poster 116Downing, J., Street, J., Hammond, L. & Darke, C. (2002)
    Identification of HLA-Cw*0409N and its distribution in blood donors resident in Wales.
    European Journal of Immunogenetics 29, 356 (2.6).
  117. View poster 117Street, J., Hammond, L., Downing, J., Thompson, J. & Darke, C. (2002)
    Sequence, genetics, serology and frequency of a new HLA-B allele B*4031.
    European Journal of Immunogenetics 29, 357 (2.10).
  118. View poster 118Street, J., Hammond, L., Downing, J., Thompson, J., Rees, T.J. & Darke, C. (2002)
    A further example of HLA-B*2712.
    European Journal of Immunogenetics 29, 358 (2.11).
  119. View poster 119Rees, M.T., Rees, T.J., Winkler, S., Eyres, R. & Darke, C. (2002)
    Repeat HLA-B27 requesting - useful or wasteful?
    European Journal of Immunogenetics 29, 360 (5.2).
  120. View poster 120Hand, S., Darke, C., Thompson, J., Stingl, C., Rolf, S., Jones, K.P., Davies, B.H. (2002)
    HLA-A, B, DR, DQ in nut allergy patients.
    European Journal of Immunogenetics 29, 360 (5.3).
  121. View poster 1121Rees, M.T., Keen, L.J., Bidwell, J.L., Darke, C. (2002)
    IFN-Gamma, TGF-ß and IL-10 cytokine polymorphisms in cadaveric kidney donors and recipients.
    European Journal of Immunogenetics 29, 362 (6.6).
  122. View poster 122Walters, R. & Darke, C. (2002)
    ELISA testing on cytotoxicity negative but flow cytometry positive renal patients' sera.
    European Journal of Immunogenetics 29, 363 (7.5).
  123. View poster 123Thompson, J., Evans, N., Harvey, C., James-Scaife, L., Eyres, R. & Darke, C. (2002)
    An analysis of 12,746 HLA-B;C haplotypes.
    European Journal of Immunogenetics 29, 366 (8.14).
  124. View poster 124Sellers, J., Coates, E., Downing, J., Walters, R. & Darke, C. (2002)
    HLA and platelet specific antibodies in patients refractory to random donor platelets.
    European Journal of Immunogenetics 29, 370 (10.11).
  125. View poster 125Darke, C. & Corbin, S. (2002)
    Accuracy of HLA-B27 typing in the United Kingdom and Republic of Ireland - 1996 - 2001.
    European Journal of Immunogenetics 29, 370 (10.12).
  126. View poster 126Johnson, J., Thompson, J., Hammond, L., Downing, J., Eyres, R., Parkes, A. B., Premawardhana, L.D.K.E., Lazarus, J.H. & Darke, C. (2002)
    HLA-A, B, DR and DQ gene and haplotype frequencies in Sri Lankan Indian Tamils.
    European Journal of Immunogenetic    s 29, 370 (10.13).
  127. View poster 127Street, J., Hammond, L., Downing, J. and Darke, C.
    A further example of HLA-Cw*0307
    European Journal of Immunogenetics 2003: 30: 316 (6.13)
  128. View poster 128Burrows, E.L. and Darke, C.
    New insights into the HLA-B14 cross-reactive group (CREG) using HLAMatchmaker.
    European Journal of Immunogenetics 2003: 30: 323 (9.11).
  129. View poster 129Street, J., Downing, J., Thompson, J., Hammond, L., Johnson, J. and Darke, C.
    Immunogenetics of six ‘rare’ HLA-B*15 alleles.
    European Journal of Immunogenetics 2003: 30: 314 (6.5).
  130. View poster 130Winkler, S., Rees, T.J. and Darke, C.
    Crude splenic lymphocytes versus splenic B-cells for renal crossmatching.
    European Journal of Immunogenetics 2003: 30: 313 (5.10).
  131. View poster 1331Thompson, J., James-Scaife, L., Downing, J. and Darke, C.
    HLA-A*0224 in ‘Welsh’ blood donors.
    European Journal of Immunogenetics 2003: 30: 316 (6.14).
  132. View poster 132Rees, T.J., Coates, E.W. and Darke, C.
    Follow-up of cytotoxicity negative, flow cytometry positive crossmatch renal transplant recipients.
    European Journal of Immunogenetics 2003: 30: 319 (8.8).
  133. View poster 133Downing, J., Thompson, J., Brown, L., Evans, N., James-Scaife, L. and Darke, C.
    High resolution HLA-B*27 typing by PCR-SSP and allele frequencies in 'Welsh' blood donors.
    European Journal of Immunogenetics 2003: 30: 315 (6.7).
  134. View poster 134Downing, J., Thompson, J. and Darke, C.
    Keeping up with new HLA alleles – a two-tier strategy to differentiate ‘ambiguity causing alleles’.
    European Journal of Immunogenetics 2003: 30: 311 (5.4).
  135. View poster 135Cleaton., A., Rees, M.T., Downing, J. and Darke, C.
    Influence of HPA-5b in renal transplantation.
    European Journal of Immunogenetics 2003: 30: 320 (8.9).
  136. View poster 136Bass, H., Street, J., Thompson, J. and Darke, C.
    A collection of EBV-transformed B-cell lines.
    European Journal of Immunogenetics 2003: 30: 323 (9.12).
  137. View poster 137Street, J., Downing, J. and Darke, C.
    Two new HLA-B alleles: B*4414 and B*5708.
    European Journal of Immunogenetics 2003: 30: 316 (6.11).
  138. View poster 138Coates, E. and Darke, C.
    One-Tube HLA-B27 typing by flow cytometry using three monoclonal antibodies.
    European Journal of Immunogenetics 2003: 30: 312 (5.8).
  139. View poster 139Walters, R., Manley, C., Harris, E., Harvey, C., Burrows, E.L. and Darke, C.
    A Study of CDC negative, flow cytometry and ELISA screen positive renal patients’ sera.
    European Journal of Immunogenetics 2003: 30: 320 (8.11).
  140. View poster 140Corbin, S. and Darke, C.
    An HLA typing ‘Educational’ Scheme operated by UK NEQAS for H & I.
    European Journal of Immunogenetics 2003: 30: 322 (9.8).
  141. View poster 141Rees, M.T., Downing, J. and Darke, C.
    MICA and MICB allele and haplotype frequencies in ‘Welsh’ blood donors.
    European Journal of Immunogenetics 2003: 30: 314 (6.4).
  142. View poster 142Johnson, J., Parkes, A.B., Premawardhana, L.D.K.E., Lazarus, J.H. and Darke, C.
    HFE and HPA in Sri Lankan Indian Tamils and Sinhalese.
    European Journal of Immunogenetics 2003: 30: 316 (6.12).
  143. View poster 143Rees, M.T., Downing, J. and Darke, C.
    MICA and MICB types of 51 International Histocompatibility Workshop cell lines.
    European Journal of Immunogenetics 2003: 30: 311 (5.5).
  144. View poster 144Rees, M.T., Downing, J. and Darke, C.
    A PCR-SSP-based MICA and MICB typing system.
    European Journal of Immunogenetics 2003: 30: 312 (5.9).
(Page Index)

Contributions to books, proceedings and newsletters:

  1. Darke, C. (1976) Ethidium bromide microcytotoxicity test. In NIAD Manual of Tissue Typing Techniques 1976-1977, eds. Ray, J.G., Hare, D.B., Pedersen, P.D. & Mullally, D.I., pp. 35-36. DHEW Publication No. (NIH) 76-545, Bethesda, Maryland.
  2. Darke, C. & Perry, W.N.C. (1979) The use of purified IgG as an antibody reagent in the lymphocytotoxic test. In NIAD Manual of Tissue Typing Techniques 1979-1980, ed. Ray, J.G., pp. 246-247. DHEW Publication No. (NIH) 80-545, Bethesda, Maryland.
  3. Mueller-Eckhardt, G., Darke, C. & Dewar, P.J. (1984) HLA- B14 cell exchange. 9th International Workshop Newsletter 5, 9-11.
  4. Mueller-Eckhardt, G., Darke, C., Fauchet, R. & Dewar, P.J. (1985) Antigen report: HLA-B14: definite splitting into Bw64 (14.1) and Bw65 (14.2). In Histocompatibility Testing 1984, eds. Albert, E.D., Baur, M.P. & Mayr, W.R., pp. 141-142. Springer-Verlag, Berlin.
  5. Mueller-Eckhardt, G., Schendel, D.J., Prel, L., Darke, C. & O'Neill, G.J. (1985) Distinct complotypes are associated with HLA-B14 subgroups. In Histocompatibility Testing 1984, eds. Albert, E.D., Baur, M.P. & Mayr, W.R., p. 610. Springer-Verlag, Berlin.
  6. Kologu, M., Fung, H., Darke, C., Richards, C.J., Hall, R.& McGregor, A.M. (1987) Post-partum thyroid dysfunction and HLA status. In: Thyroid Autoimmunity, eds. Pinchera, A., Ingbar, S.H., McKenzie, J.M. & Fenzi, G.F. pp. 441-443. Plenum Press, New York.
  7. Mills, T., Street, J. & Darke, C. (1987) Identification of an HLA-B13 variant. XIHWS Newsletter 1 (6), 8-9.
  8. Mueller-Eckhardt, G., Schroeder, M.L., Darke, C., Khan, R., Wank, R., Dejour, G., Fauchet, R., Christiansen, F., Du Toit, E., Mervart, H., Schunter, F., Stratton, A. & Sudmeyer, G. (1989) Antigen Society #7 Report (B8, w59; B14, w64, w65). In Immunobiology of HLA Vol I Histocompatibility Testing 1987, ed. Dupont, B., p. 148- 150. Springer Verlag, New York.
  9. Darke, C., Fussell, H., Street, J., Thomas, M., Kuwayama, M., Sonoda, S., Yashiki, S., Schroeder, M., Cavanagh, G., Cuccia, M. & Decary, F. (1992) Antigen society no. 107: HLA-B8, -B59, -B14, -B64, -B65, -B37. In HLA 1991 Proceedings of the Eleventh International Histocompatibility Workshop and Conference, Vol. 1, eds. Tsuji, K., Aizawa, M., Sasazuki, T., p. 308-310. Oxford University Press, New York.
  10. Reekers, P., Tiilikainen, A., Darke, C., Van der Horst, A. & McCloskey, D. (1992) Antigen society no. 111, part 2: HLA-B7-like antigens (B703(BPOT), B7Qui, BDT, B7SL, B7x40, BRI, B41V). In HLA 1991 Proceedings of the Eleventh International Histocompatibility Workshop and Conference, Vol. 1, eds. Tsuji, K., Aizawa, M., Sasazuki, T., p. 327- 330. Oxford University Press, New York.
  11. Darke, C. & Dyer, P.A. (1993) Clinical HLA typing by cytotoxicity. In: Histocompatibility Testing: A Practical Approach, eds Dyer, P.A. & Middleton, D., pp 51-80. IRL Press Practical Approach Series, Oxford.
  12. John, R., Henley, R., Parkes, A. & Darke, C. (1993) Clinical evaluation of TSH-30 assay. Proceedings of the ACB National Meeting 1993, ISSN 0959-9029, 47, A15.
  13. Worwood, M., Dorak, M.T., Raha-Chowdhury, R. & Darke, C. (1994) Genetics of Haemochromatosis. In: Progress in Iron Research, eds. Hershko, C., Konijn, A.M. & Aisen, P. Plenum Press, New York.
  14. Darke, C, McNamara, S., Guttridge, M.G. & Thompson (1997) Caucasian Welsh normal. In: HLA 1997, eds Terasaki, P.I. & Gjertson, D.W., pp 211. UCLA Tissue Typing Laboratory, Los Angeles.
  15. Finch, T., Lawlor, E., Darke, C. & S, McNamara (1997) Caucasian Irish normal. In: HLA 1997, eds Terasaki, P.I. & Gjertson, D.W., pp 212. UCLA Tissue Typing Laboratory, Los Angeles.
  16. Long, C.C., Darke, C. & Marks, R (1997) Caucasian Welsh Basal Cell Carcinoma. In: HLA 1997, eds Terasaki, P.I. & Gjertson, D.W., pp 355. UCLA Tissue Typing Laboratory, Los Angeles.
  17. Parkes, A.B., Darke, C., Othman, S., Richards, C.J., Hall, R., Lazarus, J.H. (1997) Caucasian Welsh postpartum thyroiditis. In: HLA 1997, eds Terasaki, P.I. & Gjertson, D.W., pp 355. UCLA Tissue Typing Laboratory, Los Angeles.
  18. Bonar, B.D., McColgan, B., Smith, D.F., Darke, C. & Smyth, P.P.A (1997) Caucasian Irish hypothyroidism. In: HLA 1997, eds Terasaki, P.I. & Gjertson, D.W., pp 372. UCLA Tissue Typing Laboratory, Los Angeles.
  19. Darke, C., Eyres, M.R., Howells, K., McGregor, M., McNamara, S., Powell, D., Rees, M.T., Williams, F.G. (1998) Welsh bone marrow Donor Registry - ten years on. Poster presentation "Unrelated Donor Registries - Into The Next Millennium", 23rd - 26th July, The Anthony Nolan bone marrow Trust, Royal Free Hospital, London.
  20. Bartley, M., & Darke, C. (1998) EFI accreditation inspectors come to the Welsh Blood Service. EFI Newsletter, 24, 17/21.
  21. Darke, C. (2000) Part 4 Overview - Donor Selection (Allocation of solid organs for transplantation and the selection of donors for bone marrow transplantation and HLA matched platelet transfusion). In: Histocompatibility Testing, eds Bidwell, J.L. & Navarrete, C., pp 346-348. Imperial College Press, London.
  22. Darke, C. (2001) Towards EFI accreditation: report of a meeting in London. EFI Newsletter, 33, 16-17.

Return to top (Page Index)